• Recent studies have analyzed the miRNA profile of serum

  2019-04-20

  

  Recent studies have analyzed the miRNA profile of serum and bile samples from patients with PSC and patients with CCA complicating PSC. Overall, the miRNA expression of all analyzed miRNAs from both patients with PSC and patients with CCA complicating PSC was significantly higher compared with healt

• En la condensaci n del Borges y yo

  2019-04-20

  

  En la condensación del “Borges y yo” se despliega un texto que tanto puede ser considerado perteneciente al orden de la narrativa como al orden del ensayo, e incluso al de la poesía. En palabras de José Miguel Oviedo, “es un cuento que es también un ensayo que es también un poema”. “No sé quién de l

• br Introduction Multiple signal transduction

  2019-04-20

  

  Introduction Multiple signal transduction pathways in normal and malignant nicergoline converge on Bcl-2 family proteins, which stand at the crossroads between cell survival and apoptosis. The seminal event in the intrinsic pathway of apoptosis is mitochondrial outer membrane permeabilization (M

• The points of agreement of the

  2019-04-20

  

  The points of agreement of the models in the study by Brady and colleagues make sense—eg, it is intuitive that the post-MDA prevalence of malaria is strongly related to the proportion of individuals in the NSC59984 missed by an MDA campaign, as well as the pre-MDA endemic prevalence. Although it ma

• The Sustainable Development Goals can be achieved through en

  2019-04-19

  

  The Sustainable Development Goals can be achieved through environmental prevention of diseases without an additional burden on resources. The WHO avoidable early environmental exposures initiative emphasises that the unrecognised health risks are most damaging to the human population. An absence of

• Another key challenge requires special attention in improvin

  2019-04-19

  

  Another key challenge requires special attention in improving maternal health in western China. On the basis of recent estimates, China has more than 250 million so-called rural-to-urban migrants who move from the countryside to cities to seek better paid jobs. A substantial number of these people c

• The circadian variation of VF shows

  2019-04-19

  

  The circadian variation of VF shows a similar nocturnal pattern in patients with BS and ERS [32] (Fig. 2). This is in contrast to the circadian pattern of VTAs in patients with ischemic heart diseases [33]. In a Korean cohort of patients with ERS and BS who underwent implantable cardioverter defibri

• Programmed death ligand PD L expression

  2019-04-19

  

  Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed

• The data obtained in our work showed that AMD was

  2019-04-19

  

  The data obtained in our work showed that AMD was able to inhibit complex I activity and ATP biosynthesis in MRC-5 cells. These effects were accompanied by an increase in lipid and protein oxidative damage and a decrease in NO levels and superoxide dismutase and catalase activities, suggesting that

• Vuelve a aparecer aqu la ntima

  2019-04-19

  

  Vuelve Y-27632 aparecer aquí la íntima satisfacción de un Aub cuyas obras, por expeditivas que sean —dos semanas para elaborar toda una exposición— y mediocres que puedan parecer, levantan pasiones entre los entendidos en arte porque en buena medida es a ellos, capaces de mutar la arena en oro y la

• br The Medical Education Partnership

  2019-04-19

  

  The Medical Education Partnership Initiative (MEPI) is an innovative and potentially transformative 5-year programme, established by the US Government in 2010, to increase the number of doctors to meet crucial human resource needs in sub-Saharan Africa. MEPI allows African institutions that kv1.3

• The long term goal of independence of recipients

  2019-04-19

  

  The long-term goal of independence of recipients and sustainability of projects must remain at the forefront of all programmes. The post-2015 Sustainable Development Goals (SDGs) have been criticised as being too general and impractical, and as we move into the SDG era this study has identified a ne

• Further extensive FISH and molecular studies failed to

  2019-04-18

  

  Further extensive FISH and molecular studies failed to detect either BCR–ABL, PDGFRA, PDGFRB and FGFR1 rearrangements or NPM1 and FLT3 mutations, whereas c-KIT D816V pkm2 was found on PB and BM mononuclear cells. Moreover, allele-specific PCR demonstrated JAK2 V617F mutation on both PB and BM polym

• Could new approaches to global nutrition

  2019-04-18

  

  Could new approaches to global nutrition lead to interventions that would make children grow tall without putting on excessive fat, as is the case for present-day piglets? Animal science has been addressing this issue for a long time, although with rigorous studies that cannot be conducted in humans

• We also found that the RBC folate

  2019-04-18

  

  We also found that the RBC folate level was significantly increased in individuals with the TT glucocorticoid receptor antagonist compared to individuals with the CC genotype. The plasma folate concentration fluctuates in relation to diet, and is thus a useful dynamic measure that reflects recent n

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