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br Results and discussion A systematic search for
2020-10-29
Results and discussion A systematic search for genes encoding H+-PPases was carried out by PCR using genomic DNA from a wide range of protozoa as templates and degenerate oligonucleotides, designed from amino pimaricin mg domains conserved in H+-PPases of higher plants and the proteobacterium R.
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br Materials and methods Male Hartley guinea pigs
2020-10-28
Materials and methods Male Hartley guinea pigs (300–350g) were obtained from National Laboratory Animal Center, Taiwan. LTD4, LTC4, LTE4, LTB4, montelukast and BAY u9773 were purchased from Cayman Chemical, Ann Arbor, Michigan; Carbachol, atropine, l-serine, boric acid, l-cysteine and all buffer
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br Conflicts of interest br Acknowledgements
2020-10-28
Conflicts of interest Acknowledgements This work was supported by funding from Young Sanjin Scholars Distinguished Professor, the Aid Program for Innovation Research Team in Shanxi Agricultural University (CXTD201201), and the Special Fund for Agro-scientific Research in the Public Interest of
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Trk receptors critically support the development and
2020-10-28
Trk receptors critically support the development and maintenance of the nervous system, , but their over-expression in various neural and non-neural neoplasms such as breast, pancreatic, lung and neuroendocrine tumors also confers aggressive phenotypes to tumor atp gamma s and correlates with poor p
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Alternatively procedural factors may have contributed to the
2020-10-28
Alternatively, procedural factors may have contributed to the conflicting results. For instance, in order to have a more circumscribed area of drug diffusion, a volume of 0.05μl was injected in experiment 1b, which is four times lower than the one used in the mentioned plus-maze investigation. Besid
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Recent studies showed that the activity of CK was
2020-10-28
Recent studies showed that the activity of CK2 was significantly reduced in ischemic stroke model rats, and cerebral I/R injury significantly decreased the expression of CK2α (Lee et al., 2004; Kim et al., 2012; Zhou et al., 2016). In addition, the dysregulation of CK2 is involved in ERS/UPR in non-
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The ultrafiltration approach has been used to measure equili
2020-10-28
The ultrafiltration approach has been used to measure equilibrium BIEs for a number of enzyme systems, including Sephin1 hexokinase (Lewis and Schramm, 2003a, Lewis and Schramm, 2003b), thymidine phosphorylase (Birck & Schramm, 2004), purine nucleoside phosphorylase (Murkin, Tyler, & Schramm, 2008)
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leukotriene receptor antagonist DDR although normally expres
2020-10-28
DDR2, although normally expressed in leukotriene receptor antagonist with mesenchymal features, has also been reported to enhance EMT. In A549 lung cancer cells, TGFβ1 increases the expression of type I collagen and DDR2. Knocking-down COL1A1 or DDR2 with siRNA is sufficient to inhibit EMT and cell
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Eleutherococcus senticosus Rupt Maxim Maxim is a
2020-10-28
Eleutherococcus senticosus (Rupt. & Maxim.) Maxim is a shrub belonging to the Araliaceae, which is commonly distributed in China, Korea, Japan and Russia. It has been traditionally used as folk medicine for the treatment of rheumatism, diabetes, and hepatitis (Nan et al., 2004). Recent phytochemical
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Our results suggest that formation of
2020-10-28
Our results suggest that formation of DDR1b clusters may be important for and precede receptor phosphorylation. Indeed, while DDR1b clustering was readily detected (by YFP signal) 30 min after collagen administration, phosphorylated DDR1 species at Y513 (present in the IJXM) were evident after 4 h o
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To date little is known about the regulation of
2020-10-28
To date, little is known about the regulation of PCD through phytocystatin inhibitory activity. Inhibitors that may regulate leaf senescence (Huang et al., 2001, Tajima et al., 2011) or may inhibit PCD induced by abiotic factors, such as mechanical tissue damage or oxidative stress caused by cold (B
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br Acknowledgments br Introduction Cysteinyl
2020-10-28
Acknowledgments Introduction Cysteinyl leukotrienes (CysLTs), LTC4, LTD4 and LTE4, are 5-lipoxygenase pathway metabolites of arachidonic daminozide receptor and deeply involved in bronchial asthma via activation of CysLT1 receptors [1], [2]. Specific CysLT1 receptor antagonists, including pran
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Another well established visceral action of CRF and urocorti
2020-10-27
Another well-established visceral action of CRF and urocortin administered peripherally is the long-lasting lowering of blood pressure observed in various species ranging from rodents to humans [22]. Existing evidence suggests that the hypotensive action of CRF and urocortin is mediated by the inter
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HU 308 receptor Meanwhile high levels of extraversion
2020-10-27
Meanwhile, high levels of extraversion have been associated with weaker conditioning and faster HU 308 receptor learning (Eysenck, 1970). Similar to neuroticism/anxiety, the role of extraversion for fear conditioning and extinction has found only limited empirical support (Rauch et al., 2005) with
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Flavonoids are most common and widely distributed group
2020-10-27
Flavonoids are most common and widely distributed group of natural phenolic compounds synthesized by plants that have varied effects on mammalian cell systems (Kumar and Pandey, 2013). Several studies demonstrate that flavonoids might be potent inhibitors of several protein kinases involved in vario
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