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The cardiac GP are a collection of autonomic
2019-05-16
The cardiac GP are a collection of autonomic nervous systems comprising both afferent and efferent as well as sympathetic and parasympathetic fibers [10,11]. Radiofrequency catheter ablation eliminates the most elementary level of vagal innervation by destroying the visceral efferent limb of the par
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It is noted that in this study BrS patients had
2019-05-16
It is noted that in this study BrS patients had an abnormality of plasma K+ concentration which has been suggested to be a potential trigger of Brugada Syndrome episodes [11]. In the absence of renal dysfunction, the hyperkalemia may result from an abnormal phenotype in BrS characterized by mutation
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Lead fracture was observed in of leads
2019-05-15
Lead fracture was observed in 4 of 1092 leads (0.37%); verified and incomplete lead fractures were observed in three (0.27%) and one lead (0.09%), respectively. All these fractures occurred in leads implanted by the SVP method; no fractures were observed in leads implanted by the CVC method (p Disc
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The effectiveness of the intervention varied
2019-05-15
The effectiveness of the intervention varied across districts, with the proportion of infections averted inversely related to pre-intervention consistent condom use (appendix). Understandably, for districts in which previous interventions had already led to high consistent condom use among high-risk
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In June Pakistan s military
2019-05-15
In June 2014, Pakistan\'s military operation against the Taliban in North Waziristan district of FATA, resulted in the displacement of an estimated 1 million people. The mass rora of previously unvaccinated people from North Waziristan resulted in an increased transmission of polio within Pakistan,
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Amiodarone has been used in
2019-05-15
Amiodarone has been used in Japan for more than 5 years now since its approval in July 2007, and intravenous amiodarone has been widely used for life-threatening ventricular tachycardia in the setting of critical care medicine. However, only few reports have been published in the international liter
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br Conclusion br Conflict of interest br Introduction
2019-05-15
Conclusion Conflict of interest Introduction Loss-of-function mutations in the cardiac sodium (Na+) channel gene have been implicated in Brugada syndrome, progressive cardiac conduction defect (PCCD), sick sinus syndrome, and idiopathic ventricular fibrillation (IVF) [1]. In the present stu
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ceramidase br Discussion Prehabilitation is a program to
2019-05-15
Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, and
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br In Sanguinetti et al and Barhanin et al
2019-05-15
In 1996, Sanguinetti et al. and Barhanin et al. independently found that, when coassembled with the accessory subunit KCNE1, the KCNQ1 and KCNE1 complex could form a channel that very closely exhibited conductive and kinetic properties similar to that of cardiac IKs[14,56]. Kass and coworkers subs
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As with many global health estimates data gaps contribute to
2019-05-14
As with many global health estimates, data gaps contribute to substantial uncertainty intervals. To calculate their estimates Bourne and colleagues used data from 288 studies and more than 90 countries, but data gaps persist. For example, primary data were not available for approximately half the wo
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There has been scant prior research focusing on the clinical
2019-05-14
There has been scant prior research focusing on the clinical efficiency and safety of either BV alone or in combination with chemotherapy in treating relapsed or refractory CD30+ T cell lymphoma, ALCL and HL. Although the most common and significant adverse events of BV, such as peripheral neuropath
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Obeticholic Acid br Short case report A year old man
2019-05-14
Short case report A 65-year-old man with persistent AF underwent multi-detector computed tomography (CT) before catheter ablation. An anomalous muscular band connecting the posterior side of the left atrial roof and the right edge of fossa ovalis in the left atrium was detected (Fig. 1). During
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Any abnormality causing a loss of function in the IKs
2019-05-14
Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -
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African leaders are gathering in Addis Ababa Ethiopia this
2019-05-13
African leaders are gathering in Addis Ababa, Ethiopia, this week for the first ever . The event brings together government officials, including minsters of finance, technical experts, and policymakers, with the goal of advancing the coverage of life-saving immunisations across the continent. In
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Close inspection of the tumor matrix on
2019-05-13
Close inspection of the tumor matrix on the initial and subsequent 5 month radiographs (Fig. 7), shows an atypical appearance for osteoid matrix that consistency may more closely resemble chondroid matrix. The matrix appears to display a linear dense lace-like pattern (Fig. 8). Of the only two othe
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