• Introduction Leukaemias lymphomas and multiple myeloma

  2019-05-20

  

  Introduction Leukaemias, lymphomas and multiple myeloma can be the dreadful sequelae of viral infections. RNA oncogenic viruses, which are also known as retroviruses, were initially known to cause lymphoproliferative disorders only in animals, but have also been reported to demonstrate their transf

• Clofarabine associated capillary leak syndrome

  2019-05-20

  

  Clofarabine-associated capillary leak syndrome, attributed to cytokine release, is characterized by hypotension, tachycardia, and tachypnea, and can be fatal. Alternatively, Type I hypersensitivity to clofarabine can occur in up to 5% of patients, and is also a contraindication to further therapy pe

• br The L type calcium channel LTCC in heart

  2019-05-20

  

  The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot

• br Tanto en el cuerpo

  2019-05-20

  

  Tanto en el cuerpo principal de la revista como en la sección de análisis de libros y revistas, aparecen artículos y notas de tenor necrológico, los cuales ofrecen una suerte de homenaje póstumo tsa hdac personajes que generalmente habían actuado en el terreno científico, filosófico o de gestión p

• A coordena o atestada de

  2019-05-20

  

  A coordenação atestada de valores hoje considerados universais em regulamentos, estatutos, editais e leis setoriais pelo mundo indica o esquema de convergência de motivos e razões, e figuras sociais e jurídicas, que remete a uma intensificação da comunicação entre as diversas partes do planeta, send

• When the analysis was matching with propensity

  2019-05-20

  

  When the analysis was matching with propensity score, OS was still significantly longer in JAK2+ patients (median not reached versus 73 months, p=.031) whereas JAK2 status had no significant prognostic value for OS in IPSS intermediate-2 and high patients (p=.18). Discussion In this series, whic

• muscarinic receptor antagonists Discussion Previous study ha

  2019-05-20

  

  Discussion Previous study has shown that one of the most important characteristics of music is that of reducing anxiety. The mechanism of music therapy is thought to arise from multiple nervous stimuli that are conducted into the brain, which are antagonists to each other, and under certain conditi

• br Introduction Percutaneous transcatheter device closure of

  2019-05-20

  

  Introduction Percutaneous transcatheter device closure of atrial septal defects (ASD) has become an effective alternative therapy to surgical repair in patients with secundum type ASD. Amplatzer ASD or ventricular septal defect (VSD) occluders were used for the closure of ASDs or VSDs, respective

• The clinical spectrum of intracranial hemorrhage

  2019-05-20

  

  The clinical spectrum of intracranial hemorrhage is similar for patients treated with warfarin and dabigatran [10]. Absolute rates of intracranial hemorrhage across all sites and of both fatal and traumatic intracranial hemorrhages are lower with dabigatran than with warfarin [10]. Concomitant aspir

• In this section we will try and address many of

  2019-05-20

  

  In this section we will try and address many of the frequently asked questions around preventive and prophylactic measures for patients either starting or already established on bone-targeted therapy (Figs. 2 and 3). In view of the difficulties in treating ONJ, preventive strategies would seem to ma

• br Discussion The site of the successful

  2019-05-18

  

  Discussion The site of the successful ablation was the earliest site where a TSP was recorded during tachycardia. The TSP preceded each His bundle deflection by 15ms during tachycardia, but was inverted during atrial pacing. Moreover, the TSP–His deflection interval remained unchanged at differen

• Although a well experienced group reported

  2019-05-18

  

  Although a well experienced group reported a very high success rate of 80% after catheter ablation even in patients with congestive heart failure [40], the evidence described above suggests that catheter ablation alone is not sufficient to treat AF in patients with hemodynamic deterioration. This in

• Depending on the target gene KLF may function as both

  2019-05-18

  

  Depending on the target gene, KLF4 may function as both a repressor and activator of transcription [31,32]. Previous studies demonstrated Bax could be a tumor-suppressor target of KLF4 functioning as an anti-oncogene [33,34]. When transfected with anti-miR-367, MG-63 and U2OS cannabinoid receptor s

• ICG which simply and non invasively measures

  2019-05-18

  

  ICG, which simply and non-invasively measures changes in thoracic impedance generated by fluctuating blood volumes during the cardiac cycle, allows for the calculation of stroke volume, CO, and other derived parameters[17]. In recent years, the accuracy of ICG has been greatly improved by the advent

• The Millennium Development Goals MDGs have become key target

  2019-05-18

  

  The Millennium Development Goals (MDGs) have become key targets for the international Carfilzomib over the past 15 years. The MDGs have raised awareness, focused global efforts on agreed priorities, and empowered so-called development champions at country level. This progress was less straightforwa

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