• br The Millennium Development Goals on

  2019-06-19

  

  The Millennium Development Goals on health have expanded access to basic health interventions to millions of people in low-income and middle-income countries (LMICs). However, access alone will not be sufficient to meet the Sustainable Development Goals (SDGs) if health systems cannot provide high

• br Other candidate genes br The frequency of minor gene

  2019-06-19

  

  Other candidate genes The frequency of minor gene mutations in BrS As mentioned above, more than 10 genes have been reported to cause BrS. The proportions of BrS patients who are mutation carriers, however, are very small, except in the case of SCN5A. In a recent extensive mutation analysis of

• br Benefits and tips for antitachycardia pacing To

  2019-06-19

  

  Benefits and tips for antitachycardia pacing To reduce ICD shocks, antitachycardia pacing (ATP) for terminating lethal ventricular tachyarrhythmias must be programmed. There are 2 main types of ATP: burst (scan) pacing and autodecremental overdrive pacing (ramp pacing). Programming ATP is common

• Vaccines for rotavirus and cholera the two diseases with the

  2019-06-18

  

  Vaccines for rotavirus and cholera—the two diseases with the highest child mortality rates and a significant fraction of the global diarrhoeal burden—are at preliminary stages of implementation. The use of vaccination as a global primary-prevention strategy can also be rapidly strengthened with the

• Es evidente con todo su boato

  2019-06-18

  

  Es evidente, con todo su boato, que el Corpus participa en la semántica sagrada de la celebración barroca: una ostentosa exhibición de lujo simbólico que parece insinuar, en el desperdicio de ritual y significados, en la continuidad enajenante de una metáfora explotada al máximo, el sentido sacrific

• Delays in diagnosis due to the subtlety and focal nature

  2019-06-18

  

  Delays in diagnosis due to the subtlety and focal nature of the intravascular infiltrates often lead to a terminal disease with death before chemotherapy is initiated. R-CHOP plus CNS prophylaxis is the treatment of choice in patients [30,31] without tgf beta receptor involvement. CNS involvement a

• Evidence of the efficacy of topiramate in PTC has been

  2019-06-18

  

  Evidence of the efficacy of topiramate in PTC has been reported in the literature [41,42]. The largest study, an open-label trial by Celebisoy and colleagues [41], demonstrated the non-inferiority of topiramate to acetazolamide in the management of idiopathic intracranial stat3 inhibitor in a popul

• neuronal nitric oxide synthase Demand for kidney transplanta

  2019-06-18

  

  Demand for kidney transplantation for ESKD has already outstripped the supply of donated neuronal nitric oxide synthase from living donors, notwithstanding the inadequate donor pool. End-of-life donation can potentially expand the donor pool but is less common. For example, in India, among the 12 29

• MiR a rs is situated in the

  2019-06-18

  

  MiR-196a2 rs11614913 is situated in the 3′ passenger strand mature sequence of miR-196a2. The C to T mutation of the rs11614913 SNP, which was located in the stem region of an miR-196a-2 precursor, leads to a change from a G:C to a G:U mismatch. A previous study has shown that miR-196a2 rs11614913 c

• hiv protease inhibitor br Growth supportive characteristics

  2019-06-18

  

  Growth-supportive characteristics of the BM vascular niche Similar to normal tissues, tumours also need functional blood vessels to support their growth via the delivery of oxygen and nutrients. When a DTC starts proliferating into a micrometastasis, it drives angiogenesis to build new blood vess

• br Conclusion br Conflicts of interest br

  2019-06-18

  

  Conclusion Conflicts of interest Clinical case The worldwide estimated prevalence of cardiovascular implantable electronic device (CIED) infection is 1–2%. Prompt removal of infected devices ensures survival [1–4]. We report successful extraction of a lead from an infected CIED by using an

• It is noteworthy that in a recent study

  2019-06-18

  

  It is noteworthy that in a recent study, Le Scouarnec et al. [199]. estimated the burden of rare coding variation in arrhythmia susceptibility genes among 167 BrS index patients and compared that with 167 individuals ≥65 years old with no history of cardiac arrhythmia. The authors concluded that, ex

• The participants discussed several overarching themes conclu

  2019-06-18

  

  The participants discussed several overarching themes, concluding that research is too often separate from implementation. A crucial gap remains between the development of efficacious health interventions and their optimum delivery in real-life settings. This gap is particularly true in many low-inc

• There are several limitations to the procedure described her

  2019-06-17

  

  There are several limitations to the procedure described herein. The present GC was developed for engaging the coronary sinus via a right-sided approach. However, this GC was bent dorsally and had the shortest tip and most acute tip angle among the Attain™ family, which facilitated its placement int

• To our knowledge this is the first survey to

  2019-06-17

  

  To our knowledge, this is the first survey to specifically assess, in daily clinical practice, the management of bone BIIE 0246 and, in general, the perception of bone healthcare in Italy. However, the findings of this analysis are in overall agreement with those of previous studies, some referring

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