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In the current era nearly all cases of hormone receptor
2019-04-24
In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud
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br Conclusion br Conflict of interest br
2019-04-24
Conclusion Conflict of interest Case report A 65-year-old woman with permanent atrial fibrillation was admitted with diastolic wnt inhibitor failure (HF) secondary to rapid ventricular response. She had undergone single chamber pacemaker implantation (Boston Scientific Ingenio SR) two years
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Baseline lead ECGs from immediately prior to S ICD
2019-04-24
Baseline 12-lead ECGs from immediately prior to S-ICD implantation were reviewed for all patients. Baseline intervals (PR, QRS, QT) were obtained from the automated ECG measurements. Leads I, II, and aVF were further used to collect data on QRS and T wave amplitudes, QRS/T amplitude ratio, presence
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Adem s las situaciones en las
2019-04-24
Además, las situaciones en las que Nicolás se encuentra con las piedras, sus dudas en torno pteryxin si son piedras-huesos o simples piedras, sus caminatas por cerros, encrucijadas y pueblos más o menos fantasmales, las respuestas diferentes a sus preguntas por Pedro Páramo (“¿se acuerda que yo quer
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The diagnostic infrastructure in the public sector relies ma
2019-04-24
The diagnostic infrastructure in the public sector relies mainly on sputum smear microscopy that cannot detect drug resistance. It is only when patients fail to get better on standard treatment, or have recurrence of tuberculosis, that they get screened for MDR-TB, resulting in morbidity, continued
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An urgent need therefore exists for ministries
2019-04-24
An urgent need therefore exists for ministries of health to introduce programmes for the primary and secondary prevention of rheumatic MLN 9708 manufacturer disease through their non-communicable disease programmes. The delivery of penicillin for the treatment of sore throat in children and the pre
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br Discussion In this pilot study we report that sequential
2019-04-23
Discussion In this pilot study, we report that sequential treatment of low dose clofarabine and lenalidomide is safe and feasible for elderly patients with high risk MDS and AML. Only one subject developed dose limiting toxicity (liver dysfunction) from lenalidomide consolidation therapy. Pre-tre
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br When many of us contemplate
2019-04-23
When many of us contemplate the role of agriculture in feeding 7·2 billion people, we picture large-scale, industrialised, and efficient systems that produce lots of food that is shipped around the world. Although those systems are relevant, they natural aromatase inhibitors are only one dimension
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br The world population faces various types of climate relat
2019-04-23
The world population faces various types of climate-related hazards, and both the frequency and intensity of hazards are projected to increase in the future because of climate change. Since climate change could increase human health risks, many previous studies first estimated future temperatures
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br Materials and methods br Results br Discussion
2019-04-23
Materials and methods Results Discussion To our best knowledge, a multi-modality approach to systematically characterize an OS in vivo orthotopic model, using an aggressive OS cell line has not been previously reported. The advantage of using multi-modality approach i.e. BLI, histopathology
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br Case report A year old woman who had been
2019-04-23
Case report A 41-year-old woman who had been fitted with a pacemaker for bradycardia 18 years prior presented for lead extraction on account of device infection. She had a left pectoral dual chamber pacemaker, with two tined leads: an atrial lead of 5524 M (Medtronic, Dublin, Ireland) and a ventr
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En este art culo se observar n ciertos puntos
2019-04-23
En este artículo se observarán ciertos puntos de los capítulos IX y X de Paradiso, donde el autor claramente se rehúsa Aminoallyl-dUTP - Cy3 definir a sus personajes y sus discursos, para plantear interrogantes y momentos paradigmáticos de esta imposibilidad clasificatoria que era el objetivo (o uto
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Two fundamental objections to the conclusion that
2019-04-23
Two fundamental objections to the conclusion that mass deworming for helminths has no benefits and could therefore be abandoned have been repeatedly raised. First, the underlying studies might have been insufficient to detect benefits, because the follow-up for most studies was too short to detect h
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Additionally the expression of AMH in GCs
2019-04-23
Additionally, the expression of AMH in GCs treated with BMP15 + SB203580 was significantly decreased compared with that in GCs treated with BMP15 alone; thus, it was further demonstrated that BMP15 can up-regulate the expression of AMH by activating the p38 MAPK signaling pathway. However, the expre
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br Discussion Intriguingly in a case
2019-04-23
Discussion Intriguingly, in a case report about elevation of skeletal enzymes in ultramarathon runners, the CK level reached its peak value one day after the run, had a ∼4-day plateau, and began to decline after a few more days. The sustained increase of plasma CK in this athlete was quite differ
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